Quin – KT eye drops 5 ml
Moxifloxacin & ketorolac ophthalmic solution
Composition
w/v
Ketorolac Tromethamine eq. to Ketorolac 0.5 % w/v
Moxifloxacin Hydrochloride BP
eq.to Moxifloxacin
0.5 % w/v
Benzalkonium
Chloride IP
0.01 % v/v
Sterile Aqueous vehicle q.s
Dosage form
Ophthalmic Solution
Description
Moxifloxacin
The antibacterial action of moxifloxacin results from inhibiton of the
topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential
enzyme that is involved in the replication, transcription and repair of
bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the
partitioning of the chromosomal DNA during bacterial cell division.
Ketorolac
tromethamine
Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug which, when
administered systemically, has demonstrated analgesic, anti-inflammatory, and
antipyretic activity. The mechanism of its action is thought to be due to its
ability to inhibit prostaglandin biosynthesis
Indications
The use of a combination drug with an anti-infective component is indicated
Where the risk of superficial ocular infection is high or where there is an
Expectation that potentially dangerous numbers of bacteria will be present in
the eye.
Dosage
and administration
Instill one drop in the affected eye 3 times a day or as directed by the
physician.
Contraindicationsn
Moxifloxacin and Ketorolac ophthalmic solution is contraindicated in patients
with a history of hypersensitivity to moxifloxacin, to other quinolones,
ketorolac or to any of the components in this medication.
Warnings and precautionsn
Moxifloxacin
Not for injection. :- Moxifloxacin solution should not be injected
subconjunctivally, nor should it be introduced directly into the anterior
chamber of the eye.
Ketorolac
tromethamine There is the potential for cross-sensitivity to acetylsalicylic acid,
phenylacetic acid derivatives, and other nonsteroidal anti-inflammatory agents.
Therefore, caution should be used when treating individuals who have previously
exhibited sensitivities to these drugs.
Pregnancy
Since there are no adequate and well-controlled studies in pregnant women. Quin
KT should be used during pregnancy only
if the potential benefit justifies the potential risk to the fetus.
Lactation
Caution should be exercised when QUIN
KT is administered to a nursing mother.
Pediatric Use
Not recommended below 3 years of age
Storage
Store in a cool & dark place
Presentation
Quin - KT is available in 5 ml LDP Plastic bottle ( Rexam ) pack.
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